Stefano Ghirardelli, MD

Research & Publications

Research Drives Practice.

Research is an integral part of my clinical practice. I publish in peer-reviewed international journals, contribute to leading academic textbooks, and collaborate with centers of excellence across Europe and North America. Every innovation I introduce in the operating room or clinic is grounded in solid scientific validation. Technology and new therapies can offer great value, but only when supported by robust evidence. For this reason I avoid approaches driven by current hype, treatments based on weak or absent literature, and products that quickly become "fashionable" without a real scientific rationale.

+40

Peer-reviewed publications

6

Book chapters

3

International fellowships

30+

Invited lectures

Scientific focus

Active Research Areas.

Robotic & Sensor-Guided Surgery

Clinical and biomechanical validation of robot-assisted technologies in knee replacement. Studies on the reproducibility of native kinematics and on restricted kinematic alignment.

Periprosthetic Joint Infections (PJI)

Development and dissemination of the DAPRI protocol (Debridement, Antibiotic Pearls, Retention of the Implant). Research on next-generation sequencing and nanotechnology.

Kinematics & Implant Design

Biomechanical comparison between medial pivot, posterior-stabilized, and single-radius designs. Motion analysis in collaboration with the Stanford Biomotion Laboratory.

Minimally Invasive Hip Replacement

Optimization of direct anterior and minimally invasive approaches. Functional outcomes, accelerated recovery, and reduced complications.

Selected publications

Peer-reviewed journal articles

See all on PubMed
  • J Exp Orthop · 2023

    Native knee kinematics is not reproduced after sensor guided cruciates substituting total knee arthroplasty

    Indelli PF, Giuntoli M, Zepeda K, Ghirardelli S, Valtanen RS, Iannotti F.

  • Arthroplasty · 2023

    Biomechanical considerations for an easily-restricted robot-assisted kinematic alignment

    Valpiana P, Ghirardelli S, Valtanen RS, Risitano S, Iannotti F, Schaller C, Zepeda K, Engl M, Indelli PF.

  • Journal of Functional Morphology Kinesiology · 2021

    Kinematic comparison between medially-congruent and posterior-stabilized third generation TKA designs

    Ghirardelli S, Asay JL, Leonardi EA, Amoroso T, Andriacchi TP, Indelli PF.

  • J Orthop Surg (Hong Kong) · 2020

    Sensor Guided Technology Helps to Reproduce Medial Pivot Kinematics in Total Knee Arthroplasty

    Cochetti A, Ghirardelli S, Iannotti F, Risitano S, Giardini P, Indelli PF.

  • Knee Surg Sports Traumatol Arthrosc · 2020

    No clinical differences at 2-year follow-up between single radius and J-curve medial pivot total knee arthroplasty

    Indelli PF, Morello F, Ghirardelli S, Fidanza A, Iannotti F, Ferrini A.

  • JBJS Reviews · 2019

    Intraoperative Sensing Technology to Achieve Balance in Primary TKA: A Review of the Literature

    Ghirardelli S, Bala A, Peretti G, Antonini G, Indelli PF.

  • Hip International · 2020

    Debridement, Antibiotic Pearls, and Retention of the Implant (DAPRI) in infected Total Hip Arthroplasty

    Ghirardelli S, Fidanza A, Prati P, Iannotti F, Indelli PF.

  • Pathogens · 2023

    Debridement, Antibiotic Pearls, and Retention of the Implant (DAPRI) in Early Periprosthetic Joint Infections

    Indelli PF, Ghirardelli S, Valpiana P, Bini L, Festini M, Iannotti F.

  • EFORT Open Reviews · 2021

    Next-Generation Sequencing for Pathogen Detection in Periprosthetic Joint Infections

    Indelli PF, Ghirardelli S, Violante B, Amanatullah DF.

  • Tropical Medicine and Infectious Disease · 2021

    Nanotechnology as an Anti-Infection Strategy in Periprosthetic Joint Infections (PJI)

    Indelli PF, Ghirardelli S, Iannotti F, Indelli AM, Pipino G.

Book chapters

Contributions to academic textbooks.

Varus-Valgus correction deformity in total knee arthroplasty

Knee Arthroplasty (SIAGASCOT Monographs)

Edra Edizioni · 2022

Osteoarthritis of the knee and total knee arthroplasty

Orthopedics and Trauma: Current Concepts and Best Practices

Springer New York · 2022

Effect of Tradition and Innovation on the Technique of Total Knee Arthroplasty

ESSKA/EKA/EHS/AAHKS Lecture Book

Springer New York · 2022

Total hip arthroplasty surgical approaches: optimizing the outcome

ESSKA/EKA/EHS/AAHKS Lecture Book

Springer New York · 2022

International network

Academic Collaborations.

A network of world-leading centers that fuels scientific exchange, translational research, and continuous refinement of surgical techniques.

  • Stanford University

    Department of Orthopaedic Surgery, Biomotion Laboratory

    Stanford, USA

  • Hospital for Special Surgery (HSS)

    Adult Reconstruction & Joint Replacement Service

    New York, USA

  • University of Toronto

    Mount Sinai Hospital, Lower Extremity Reconstruction

    Toronto, Canada

Professional memberships

Professional Societies.

Member of international societies dedicated to hip and knee surgery and orthopedic sports medicine.

  • AAHKS

    American Association of Hip and Knee Surgeons

    Member

  • ESSKA

    European Society of Sports Traumatology, Knee Surgery and Arthroscopy

    Member

  • SIAGASCOT

    Italian Society of Arthroscopy, Knee, Sport, Cartilage and Orthopaedic Technologies

    Member

  • AAOS

    American Academy of Orthopaedic Surgeons

    International Member

  • AOSSM

    American Orthopaedic Society for Sports Medicine

    International Member

Editorial activity

Reviewer for peer-reviewed journals.

  • , Journal of Experimental Orthopedics
  • , BMC Musculoskeletal Disorders
  • , Journal of Orthopaedic Experience & Innovation
  • , Surgery Insights (Editorial Board)

Faculty & speaker

Meetings & Training Courses.

  • Invited speaker at AAHKS, ESSKA, and SIAGASCOT meetings.
  • Faculty in international robotic knee surgery courses.
  • Cadaver-lab instructor for minimally invasive hip approaches.
  • Clinical tutor for Italian and international fellows and residents.

Would you like the full publication list?

Available on PubMed, Google Scholar, or by direct request.